Residual solvent screening identifies trace solvents remaining from botanical extraction processes, helping ensure products are solvent-free, safe for consumers, and compliant with ICH and workplace safety regulations.
When solvents are used to extract compounds from plant material, trace amounts of those solvents can unintentionally remain in the finished product. These residual solvents may pose safety risks and must be monitored before products are released to market.
Working with Vanguard Laboratory helps ensure that botanical products are solvent-free and meet both internal quality standards and regulatory requirements.
Excluding ethanol, allowable limits for solvent residues in botanical products are defined by the International Conference on Harmonization (ICH).
Extremely hazardous solvents including known or suspected human carcinogens. The ICH recommends avoiding these solvents entirely during production.
Solvents with lower toxicity and a permitted exposure limit of 50 mg per day. Residual solvent content must not exceed 0.5 percent by weight.
The Baseline of Truth
The Safety Standard
The Industry Apex
5-8 days for purity/quantity testing. Sterility takes 15 days. Rush options available.
