Peptide characterization

Intact mass, sequence confirmation, peptide mapping, impurity identification, content, counter-ion, water, aggregates, stability and method validation, on the same instruments as our routine peptide testing. For compounders, manufacturers and research groups.

Services

Quoted

Measured molecular mass of the intact peptide against the theoretical mass for the sequence. Details

Quoted

Fragment-ion evidence that the peptide has the stated sequence. Details

Quoted

Enzymatic digest and LC-MS/MS to confirm primary structure and locate modifications on peptides and proteins. Details

Quoted

Profile of impurities above the reporting threshold, with mass assignment of each. Details

Included in Silver, Gold and Elite for vials. Content on powders is quoted.

Amount of peptide per vial or per gram, against a qualified reference standard. Details

Quoted

Trifluoroacetate or acetate content of the peptide salt. Details

Quoted

Water content of lyophilized material, for net peptide content. Details

Included with purity for somatropin at $250. Other proteins quoted.

Dimer and higher molecular weight species in proteins and peptides. Details

Quoted

Purity, content and appearance at defined time points under stated storage conditions. Details

Quoted

Development and validation of HPLC and LC-MS methods for a specific peptide or preparation. Details

Quoted

Sub-visible particle counts in injectable preparations. Details

How it works

Send the sequence, modifications and the question you need answered. We confirm the approach, the sample amount and the price before any work starts. Routine services report in 3 to 5 business days; studies run to the agreed protocol.

Order

Start an order online, or send the compound name and the tests you need for a quote.