MK-677 (ibutamoren) is an orally active, non-peptide growth hormone secretagogue developed by Merck as L-163,191; it is usually supplied as the mesylate salt[1, 2, 3].
MK-677 (ibutamoren) testing at Vanguard Laboratory: purity, quantity and identity from $250 per sample. Results in 3 to 5 business days; sterility 14 days.
On this page: Testing · Compound data · Structure and names · Research · Analytical notes · USP–NF · References
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? We run other tests on request.
Table scrolls sideways on small screens.
| Test | Purpose for this compound | Reported as | Sample | Turnaround |
|---|---|---|---|---|
| Purity and quantity | Purity and quantity per unit against the label claim, for the stated salt form. Impurity peaks are reported; identifying them is a separate request. | Purity, area percent, two decimals. Quantity, mg per unit, with label claim. | 1 sample unit; contact the laboratory about quantity for the submitted format. | 3 to 5 business days from receipt. |
| Identity | Routine identity: retention time and UV spectrum against a reference standard. It does not establish stereochemistry. | Match or no match, with the basis stated. | No additional sample unit. | 3 to 5 business days, with purity and quantity. |
| LC-MS identity | A matching mass (monoisotopic 528.24 Da, free base) supports the expected composition. It does not establish enantiomeric purity. It helps distinguish MK-677 from unrelated substitutes of different mass. Quoted separately. | Observed mass, expected mass, mass spectrum. | Confirm sample quantity and the compound list before shipping. | 3 to 5 business days from receipt. |
| Heavy metals | Arsenic, cadmium, chromium, mercury and lead in bulk powder or capsules. | Each element with result and detection or quantitation limit. | 1 extra unit. | 3 to 5 business days from receipt. |
| Residual solvents | Solvents from synthesis or capsule filling in the bulk material. | Each solvent with result and reporting limit. | Sample amount depends on the form (powder, capsule or liquid) and scope; contact the laboratory before shipping. | 3 to 5 business days from receipt. |
| Raw powder purity | Purity of the bulk powder before encapsulation. | Purity, area percent, two decimals. Chromatogram. | 50 mg in a sealed container, labeled with material name and lot. | 3 to 5 business days from receipt. |
What these results do not show: results describe the sample tested. Purity and content do not establish biological activity, sterility, or the absence of contaminants that were not tested.
MK-677 (ibutamoren): 2D structure drawn from the PubChem record. Stereochemistry shown as registered.
non-peptide spiroindoline growth hormone secretagogue (small molecule)
C27H36N4O5S (free base); mesylate C28H40N4O8S2
528.7 g/mol (free base); 624.8 (mesylate)
Monoisotopic 528.24 Da (free base)
159634-47-6
IUPAC name: 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
Stereochemistry: One stereocenter, (R)
CAS note: Free base; the mesylate is 159752-10-0.
Other names: Ibutamoren, MK-0677, L-163,191, Ibutamoren mesylate
PubChem CID 178024 · UNII GJ0EGN38UL[1, 2]
Structural features:
Not approved as a drug in the US. FDA lists ibutamoren mesylate among bulk substances that may present significant safety risks, citing potential congestive heart failure and a hip-fracture trial terminated early for that signal[4].
Summaries of published research, for reference only. Not a claim of safety or efficacy.
No official USP–NF monograph for MK-677 (ibutamoren) was identified in the public sources checked.
Start an order online, or send the compound name and the tests you need for a quote.
