Alkaloid and Methylxanthine Assays

Yohimbine and rauwolscine, huperzine A, mitragynine, mesembrine and oxindole alkaloids, other indole alkaloids, isoquinoline alkaloids such as those of California poppy and greater celandine, synephrines and methylxanthines.

Data sheet

TestsYohimbine, alpha-yohimbine, huperzine A, mitragynine, mesembrine alkaloids, oxindole alkaloids, alstonine, reserpine, flavopereirine, California poppy alkaloids, alkaloids as chelidonine, p- and m-synephrine, paraxanthine, theobromine, xanthines
MethodHPLC or UPLC; UV for the chelidonine estimate
ResultsReported against your specification or label claim, with pass/fail where limits apply.
PriceQuoted per project

How it works

The chromatographic tests separate the named compounds and measure them against reference standards. The chelidonine UV test is a group estimate, described in its section.

Several of these compounds are stereoisomers or positional isomers of each other. They are separated, and reported individually or as a sum, as your specification states.

Tests offered

Yohimbine HCl content by HPLC

Measures yohimbine, an indole alkaloid, by HPLC and reports it as yohimbine hydrochloride where the specification is stated that way.

Alpha-yohimbine (rauwolscine) HCl content by HPLC

Measures alpha-yohimbine, also called rauwolscine, a stereoisomer of yohimbine, by HPLC as its own compound.

Yohimbine HCl and alpha-yohimbine HCl content by HPLC

Measures yohimbine and alpha-yohimbine together by HPLC and reports each.

Huperzine A content by HPLC

Measures huperzine A, an alkaloid from Huperzia serrata, by HPLC as a single compound.

Mitragynine content by HPLC

Measures mitragynine, an indole alkaloid of Mitragyna speciosa (kratom), by HPLC as a single compound.

Mesembrine alkaloids content by UPLC

Measures mesembrine-type alkaloids, such as those of Sceletium tortuosum, by UPLC. Tell us which alkaloids your specification names.

Oxindole alkaloids content by UPLC

Measures oxindole alkaloids, for example in cat's claw (Uncaria tomentosa), by UPLC. Tell us which alkaloids your specification names and whether it states each or a total.

Alstonine content by HPLC

Measures alstonine, an indole alkaloid, by HPLC as a single compound.

Alstonine and reserpine content by HPLC

Measures alstonine and reserpine, two indole alkaloids, together by HPLC and reports each.

Flavopereirine content by HPLC

Measures flavopereirine, an alkaloid, by HPLC as a single compound. Tell us the material.

Alkaloids content in California poppy by HPLC

Measures alkaloids in California poppy (Eschscholzia californica) materials by HPLC. Tell us which alkaloids your specification names.

Alkaloids as chelidonine by UV

A UV estimate of alkaloids expressed as chelidonine, for example in greater celandine (Chelidonium majus) materials. It is a response-based group result that does not identify individual alkaloids.

p-Synephrine and m-synephrine (phenylephrine) content by HPLC

Measures p-synephrine and m-synephrine (also called phenylephrine), positional isomers, by HPLC and reports each, or their sum where your specification states one. Tell us the material, for example bitter orange extract.

Paraxanthine content by HPLC

Measures paraxanthine, a dimethylxanthine, by HPLC as a single compound.

Theobromine content by HPLC

Measures theobromine, a methylxanthine found in cocoa, by HPLC as a single compound.

Xanthines content by HPLC

Measures methylxanthines, such as caffeine, theobromine and theophylline, by HPLC. Tell us which xanthines your specification names and whether it states each or a total.

Sending samples

Send the material sealed, labeled and protected from light.

Tell us the material or extract, the form specified (for example the hydrochloride salt) and the label claim or specification. We confirm the sample amount at quote.

Questions

Questions about a sample or a method, call 360-967-7010 or email [email protected].