Progesterone

Progesterone: steroid hormone.

Purity and quantity by the chromatographic method matched to the compound (HPLC-UV, LC-MS or GC-MS), with identity against a reference standard. $250 per sample; raw powder purity $200. Results in 3 to 5 business days.

Structure

Progesterone: 2D structure drawn from the PubChem record (CID 5994).

Compound data

CAS number

57-83-0

Formula

C₂₁H₃₀O₂

Molecular weight

314.5 g/mol (monoisotopic 314.22)

Type

steroid hormone

Structure and names

IUPAC name: (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Other names: pregn-4-ene-3,20-dione

How Vanguard tests Progesterone

Identity, purity and quantity are measured by the chromatographic method matched to the compound (HPLC-UV, LC-MS or GC-MS) against a reference standard, $250 per sample with results in 3 to 5 business days.

Full testing to the USP Progesterone monograph is available and quoted: identification by infrared absorption and assay by HPLC with UV detection.

What's reported

Purity, as percent of total peak area
Quantity, in mg per unit or % w/w against the label
Identity, reported as match or no match against the reference standard
With full monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days.

Salts, forms and compendial references

A USP monograph exists for Progesterone. Full monograph testing is quoted.
Tell us the salt or form the label states, so quantity is reported on the same basis.
One page covers Progesterone and its salts and forms.

Questions about Progesterone testing

Can you test progesterone in a cream?

Yes, as a finished product. Sample preparation is matched to the cream base, and quantity is reported as % w/w or mg per gram against the label.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Progesterone monograph adds the monograph's own tests and is quoted.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/5994

Order

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