Glycerol (HydroMax)

Glycerol: triol.

Glycerol testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Glycerol

Glycerol: 2D structure drawn from the PubChem record (CID 753).

Compound data

CAS number

56-81-5

Formula

C3H8O3

Molecular weight

92.09 g/mol (monoisotopic 92.05)

Type

triol

Structure and names

IUPAC name: propane-1,2,3-triol

Other names: glycerin, HydroMax (trade name of a glycerol powder)

How Vanguard tests Glycerol

Identity, purity and quantity are measured against a reference standard by a chromatographic assay, with detection selected for the compound, $250 per sample with results in 3 to 5 business days. Finished products use the same approach, with sample preparation matched to the product.

Full testing to the USP Glycerin monograph is available and quoted; see USP monograph: Glycerin (glycerol) below.

What's reported

  • Purity, as percent of total peak area
  • Quantity, in mg per serving or % w/w against the label
  • Identity, reported as match or no match against the reference standard

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • A USP monograph exists for Glycerin. Monograph testing is quoted.
  • Tell us the salt or form the label states, so quantity is reported on the same basis.
  • One page covers Glycerol and its salts and forms.

Questions about Glycerol testing

Glycerol has no UV absorbance. How is it measured?

By a chromatographic assay, with detection selected for the compound, against a glycerol reference standard; powdered glycerol products are reported as % glycerol against the label.

Can you test it in a finished product?

Yes. Capsules, powders, gummies and liquids are measured with sample preparation matched to the product, and reported in mg per serving or % w/w against the label.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Glycerin monograph adds the monograph's own tests and is quoted.

USP monograph: Glycerin (glycerol)

The USP monograph covers identity by infrared spectroscopy and a diethylene glycol and ethylene glycol limit by chromatography, assay by titration, chloride, sulfate, residue on ignition, related compounds by chromatography, chlorinated compounds, fatty acids and esters by titration, color, specific gravity, and water content.

Forms and titles: Glycerin (CAS 56-81-5)

Why does the glycerin monograph check for diethylene glycol?

Diethylene glycol and ethylene glycol look and behave like glycerin and have been substituted for it in the past. They differ in mass and separate in the chromatographic test, which is why the check is part of identification.

Why is glycerin hard to detect by UV?

Glycerin is a small polyol with no chromophore. It absorbs almost no UV light, so the lab uses a detection method suited to the compound.

What form do glycerin samples usually come in?

Samples are a clear, thick liquid, from plant oils or made synthetically. It takes up water from air, so containers should be full and tightly closed, and water content is reported with the assay.

Order

Send the product name, the form of the ingredient and the label claim for a quote, or submit a sample with the sample form.