Orlistat

Orlistat: lipase inhibitor.

Orlistat testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Orlistat: 2D structure drawn from the PubChem record (CID 3034010).

Compound data

CAS number

96829-58-2

Formula

C₂₉H₅₃NO₅

Molecular weight

495.7 g/mol (monoisotopic 495.39)

Type

lipase inhibitor

Structure and names

IUPAC name: [(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-4-methylpentanoate

How Vanguard tests Orlistat

Identity, purity and quantity are measured by a chromatographic assay, with detection selected for the compound, against a reference standard, $250 per sample with results in 3 to 5 business days. Finished products use the same approach, with sample preparation matched to the product.

Full testing to the USP Orlistat monograph is available and quoted: identification by infrared absorption and HPLC, assay by HPLC, and impurities by thin-layer chromatography, gas chromatography and HPLC.

What's reported

Purity, as percent of total peak area
Quantity, in mg per serving or % w/w against the label
Identity, reported as match or no match against the reference standard

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

A USP monograph exists for Orlistat. Monograph testing is quoted.
Tell us the salt or form the label states, so quantity is reported on the same basis.
One page covers Orlistat and its salts and forms.

Questions about Orlistat testing

How should orlistat samples be sent?

Sealed, dry and cool. Orlistat is sensitive to heat and moisture, and its breakdown products separate by HPLC.

Can you test it in a finished product?

Yes. Capsules, powders, gummies and liquids are measured with sample preparation matched to the product, and reported in mg per serving or % w/w against the label.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Orlistat monograph adds the monograph's own tests and is quoted.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/3034010

Order

Send the product name, the form of the ingredient and the label claim for a quote, or submit a sample with the sample form.

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