Dexpanthenol (provitamin B5)

Dexpanthenol: provitamin B5 (alcohol of pantothenic acid).

Dexpanthenol testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Dexpanthenol

Dexpanthenol: 2D structure drawn from the PubChem record (CID 131204).

Compound data

CAS number

81-13-0

Formula

C9H19NO4

Molecular weight

205.25 g/mol (monoisotopic 205.13)

Type

provitamin B5 (alcohol of pantothenic acid)

Structure and names

IUPAC name: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide

Other names: D-panthenol, provitamin B5

How Vanguard tests Dexpanthenol

Identity, purity and quantity are measured by reversed-phase HPLC with UV detection against a reference standard, $250 per sample with results in 3 to 5 business days. Finished products use the same approach, with sample preparation matched to the product.

Full testing to the USP Dexpanthenol monograph is available and quoted: identification by infrared absorption and chemical tests, assay by titration, and impurities by titration.

What's reported

  • Purity, as percent of total peak area
  • Quantity, in mg per serving or % w/w against the label
  • Identity, reported as match or no match against the reference standard

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • A USP monograph exists for Dexpanthenol. Monograph testing is quoted.
  • Tell us the salt or form the label states, so quantity is reported on the same basis.
  • One page covers Dexpanthenol and its salts and forms.

Questions about Dexpanthenol testing

Dexpanthenol or DL-panthenol?

Routine HPLC does not separate the D and L forms; chiral purity is an add-on ($250 where a chiral method exists). Creams and solutions are measured with sample preparation matched to the formula.

Can you test it in a finished product?

Yes. Capsules, powders, gummies and liquids are measured with sample preparation matched to the product, and reported in mg per serving or % w/w against the label.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Dexpanthenol monograph adds the monograph's own tests and is quoted.

Order

Send the product name, the form of the ingredient and the label claim for a quote, or submit a sample with the sample form.