Aloe latex: botanical (dried leaf latex).
Aloe latex testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Marker compound: 2D structure drawn from the PubChem record (CID 12305761).
Aloe
aloin A (barbaloin, CAS 1415-73-2), aloin B
total or named markers, as your specification states
Botanical (dried leaf latex)
Marker compounds: aloin A (barbaloin, CAS 1415-73-2), aloin B
Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (aloin A, aloin B), LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by color reactions and HPTLC, content of aloin by HPLC, and gravimetric tests for extractive, ash, alcohol-insoluble matter and loss on drying, plus pesticide residues. Full testing to the USP Aloe monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for the marker compounds (aloin A and aloin B), and LC-MS for identity. Full testing to the USP Aloe monograph is available and quoted.
No. The USP article is the dried latex, the bitter yellow sap from just under the leaf skin, which is rich in aloin. Inner leaf gel has little aloin, so the two give very different results.
Aloin A and its isomer aloin B are the main anthrone glycosides in the latex and the monograph's content marker. The same assay is often used to confirm that decolorized gel products have had the latex removed.
The monograph covers Aloe vera, Aloe ferox and their hybrids. They share aloin as the main marker, though the overall profile can differ between species.
https://pubchem.ncbi.nlm.nih.gov/compound/12305761
Identity facts from the USP monograph header for this compound.
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