Citalopram hydrobromide

Citalopram hydrobromide: selective serotonin reuptake inhibitor (SSRI).

Citalopram hydrobromide testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Citalopram hydrobromide

Citalopram hydrobromide: 2D structure drawn from the PubChem record (CID 77995).

Compound data

CAS number

59729-32-7

Formula

C20H21FN2O · HBr

Molecular weight

405.30 g/mol

Type

Selective serotonin reuptake inhibitor (SSRI)

Structure and names

Identity: Citalopram hydrobromide

IUPAC name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;hydrobromide

How Vanguard tests Citalopram hydrobromide

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, HPLC retention time and a bromide test, assay by HPLC, organic impurities by HPLC, plus residue on ignition, optical rotation, pH, water content and completeness of solution. Full testing to the USP Citalopram Hydrobromide monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Citalopram
  • Citalopram Hydrobromide (CAS 59729-32-7)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Citalopram hydrobromide testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay and LC-MS for identity. Full testing to the USP Citalopram Hydrobromide monograph is available and quoted.

Can the test tell citalopram from escitalopram?

Not by standard reversed-phase HPLC or LC-MS, because the two have the same mass and retention time. Escitalopram is the S-enantiomer of citalopram, so telling them apart needs a chiral method, which is quoted separately.

Is the result reported as citalopram or as the hydrobromide salt?

The monograph assays citalopram hydrobromide, and a free base figure can be calculated from the molecular weights. Oral solutions and tablets are usually reported as percent of the label claim, which is normally stated as citalopram base.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/77995

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.