Citalopram hydrobromide: selective serotonin reuptake inhibitor (SSRI).
Citalopram hydrobromide testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Citalopram hydrobromide: 2D structure drawn from the PubChem record (CID 77995).
59729-32-7
C20H21FN2O · HBr
405.30 g/mol
Selective serotonin reuptake inhibitor (SSRI)
Identity: Citalopram hydrobromide
IUPAC name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;hydrobromide
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy, HPLC retention time and a bromide test, assay by HPLC, organic impurities by HPLC, plus residue on ignition, optical rotation, pH, water content and completeness of solution. Full testing to the USP Citalopram Hydrobromide monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay and LC-MS for identity. Full testing to the USP Citalopram Hydrobromide monograph is available and quoted.
Not by standard reversed-phase HPLC or LC-MS, because the two have the same mass and retention time. Escitalopram is the S-enantiomer of citalopram, so telling them apart needs a chiral method, which is quoted separately.
The monograph assays citalopram hydrobromide, and a free base figure can be calculated from the molecular weights. Oral solutions and tablets are usually reported as percent of the label claim, which is normally stated as citalopram base.
https://pubchem.ncbi.nlm.nih.gov/compound/77995
Identity facts from the USP monograph header for this compound.
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