Deoxycholic acid

Deoxycholic acid: bile acid.

Deoxycholic acid testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Deoxycholic acid

Deoxycholic acid: 2D structure drawn from the PubChem record (CID 222528).

Compound data

CAS number

83-44-3

Formula

C24H40O4

Molecular weight

392.58 g/mol

Type

Bile acid

Structure and names

Identity: Deoxycholic acid

IUPAC name: (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

How Vanguard tests Deoxycholic acid

Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, lead by atomic absorption, residue on ignition, optical rotation, water, solution clarity and color, bacterial endotoxins and microbial limits. Full testing to the USP Deoxycholic Acid monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Deoxycholic Acid (CAS 83-44-3)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Deoxycholic acid testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Deoxycholic Acid monograph is available and quoted.

Why is a standard UV detector not used for deoxycholic acid?

Bile acids have almost no UV chromophore, so the lab uses a detection method suited to the compound.

What impurities show up in deoxycholic acid?

Other bile acids, such as cholic acid, and isomers of deoxycholic acid are the usual related compounds. Several share a mass with deoxycholic acid, so chromatographic separation matters.

Is deoxycholic acid the same as ursodiol?

No. They have the same formula, C24H40O4, but the hydroxyl groups sit in different positions. HPLC retention time tells them apart, even though they have the same mass.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/222528

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.