Esomeprazole magnesium: proton pump inhibitor (benzimidazole).
Esomeprazole magnesium testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Esomeprazole magnesium: 2D structure drawn from the PubChem record (CID 21121303).
217087-09-7
(C17H18N3O3S)2Mg · 3H2O
767.17 g/mol
Proton pump inhibitor (benzimidazole)
Identity: Esomeprazole magnesium trihydrate
IUPAC name: magnesium;bis(5-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide);trihydrate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monographs cover identity by infrared spectroscopy, UV absorbance and HPLC retention time, assay by HPLC, organic impurities by HPLC and enantiomeric purity by chiral HPLC, magnesium by atomic absorption or strontium by titration, plus water content and color of solution. Full testing to the USP Esomeprazole Magnesium monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay and LC-MS for identity. Full testing to the USP Esomeprazole Magnesium monograph is available and quoted.
USP recognizes the trihydrate and the dihydrate, and they have different molecular weights. Tell us the form on your label so the assay is calculated on the right basis.
Not with the standard method, because esomeprazole is the S-enantiomer of omeprazole. The monograph checks enantiomeric purity by chiral HPLC, which is quoted separately.
No. The $250 test measures the esomeprazole itself. The monograph's magnesium or strontium content test is part of full monograph testing.
https://pubchem.ncbi.nlm.nih.gov/compound/21121303
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
