Five-leaved chaste tree: botanical (leaf).
Five-leaved chaste tree testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Marker compound: 2D structure drawn from the PubChem record (CID 442416).
Vitex negundo Leaf
agnuside, negundoside
total or named markers, as your specification states
Botanical (leaf)
Marker compounds: agnuside (CAS 11027-63-7), negundoside
Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (agnuside, negundoside), LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of agnuside and negundoside by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Vitex negundo leaf is available and quoted.
$250
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for the marker compounds (agnuside and negundoside), and LC-MS for identity. Full testing to the USP Herbal Medicines Compendium monograph for Vitex negundo leaf is available and quoted.
They are iridoid glycosides, and the monograph sets the leaf's quality as the sum of the two. A low total can mean old or poorly stored leaf, or a different plant.
No. Chasteberry is the fruit of Vitex agnus-castus, a related species. Agnuside is found in both, but negundoside is characteristic of Vitex negundo, so the marker pattern helps tell them apart.
Dried leaf, leaf powder and leaf extracts all have their own monographs. Extracts are concentrated, so let us know the form so results are reported on the right basis.
https://pubchem.ncbi.nlm.nih.gov/compound/442416
Identity facts from the USP monograph header for this compound.
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