Fo-ti: botanical (root, stilbene and anthraquinone markers).
Fo-ti testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Marker compound: 2D structure drawn from the PubChem record (CID 5321884).
Polygonum multiflorum Root
2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside, emodin, physcion, emodin-8-O-β-D-glucoside
total or named markers, as your specification states
Botanical (root, stilbene and anthraquinone markers)
Marker compounds: 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (CAS 82373-94-2), emodin (CAS 518-82-1), physcion (CAS 521-61-9), emodin-8-O-β-D-glucoside
Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (stilbene glucoside and anthraquinones), LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside and total anthraquinones by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Polygonum multiflorum Root is available and quoted.
$250
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of stilbene glucoside and anthraquinones, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Polygonum multiflorum Root is available and quoted.
Fo-ti contains anthraquinones such as emodin and physcion along with the stilbene glucoside, and the monograph sets content for both. Processing the root with black bean juice lowers the anthraquinone glycosides.
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside is the main characteristic marker of fo-ti root. It can isomerize from trans to cis in light, so samples are protected from light.
https://pubchem.ncbi.nlm.nih.gov/compound/5321884
Identity facts from the USP monograph header for this compound.
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