Forsythia fruit (Forsythia suspensa)

Forsythia fruit: botanical (fruit, lignan markers).

Forsythia fruit testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Marker compound: 2D structure drawn from the PubChem record (CID 5281773).

Compound data

Botanical source

Forsythia suspensa Fruit

Marker compounds

forsythoside A, phillyrin, phillygenin, pinoresinol and lariciresinol

Basis

total or named markers, as your specification states

Type

Botanical (fruit, lignan markers)

Structure and names

Marker compounds: forsythoside A (CAS 79916-77-1), phillyrin (CAS 487-41-2), phillygenin (CAS 487-39-8), pinoresinol (CAS 487-36-5) and lariciresinol

How Vanguard tests Forsythia fruit

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (forsythoside A and lignans), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of forsythoside A, phillyrin, phillygenin, pinoresinol and lariciresinol by HPLC.

What's reported

Marker compounds, as % w/w on the basis your specification states
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Forsythia suspensa Fruit
Forsythia suspensa Fruit Powder
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Forsythia fruit testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of forsythoside A and lignans, with LC-MS identity. The USP Herbal Medicines Compendium monograph for Forsythia suspensa Fruit is still in development; testing against it is available and quoted.

Is green forsythia fruit different from ripe fruit?

Forsythia fruit is sold as green fruit and as ripe fruit. Green fruit is usually higher in forsythoside A, so the marker profile can show which was used.

Why are phillyrin and phillygenin both measured?

Phillygenin is the aglycone of phillyrin, and hydrolysis during processing or storage shifts the balance from phillyrin to phillygenin.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/5281773

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.

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