Homosalate

Homosalate: sunscreen UV filter (salicylate ester).

Homosalate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Homosalate: 2D structure drawn from the PubChem record (CID 8362).

Compound data

CAS number

118-56-9

Formula

C₁₆H₂₂O₃

Molecular weight

262.34 g/mol

Type

Sunscreen UV filter (salicylate ester)

Structure and names

Identity: Homosalate

IUPAC name: (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate

How Vanguard tests Homosalate

Method for the $250 identity, purity and quantity test: GC-FID assay and purity, GC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, assay by GC, specific gravity and refractive index. Full testing to the USP Homosalate monograph is available and quoted.

What's reported

Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Homosalate (CAS 118-56-9)
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Homosalate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by GC-FID for assay and purity, and GC-MS for identity. Full testing to the USP Homosalate monograph is available and quoted.

Why does homosalate show two peaks?

Homosalate is a mix of cis and trans isomers of the trimethylcyclohexyl ester. The USP GC assay resolves both, and the total is reported.

Is homosalate the same as octisalate?

No. Both are salicylate esters used as UV filters, but octisalate is the 2-ethylhexyl ester. They have different masses and GC retention times.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/8362

Identity facts from the USP monograph header for this compound.

Order

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