Korean angelica (Angelica gigas)

Korean angelica: botanical (coumarin-containing root).

Korean angelica testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Marker compound: 2D structure drawn from the PubChem record (CID 442126).

Compound data

Botanical source

Angelica gigas Root

Marker compounds

decursin, decursinol angelate, demethylsuberosin

Basis

total or named markers, as your specification states

Type

Botanical (coumarin-containing root)

Structure and names

Marker compounds: decursin (CAS 5928-25-4), decursinol angelate (CAS 130848-06-5), demethylsuberosin

How Vanguard tests Korean angelica

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (decursin, decursinol angelate and demethylsuberosin), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of decursin, decursinol angelate and demethylsuberosin by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Angelica gigas Root is available and quoted.

What's reported

Marker compounds, as % w/w on the basis your specification states
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Angelica gigas Root
Angelica gigas Root Powder
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Korean angelica testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of decursin, decursinol angelate and demethylsuberosin, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Angelica gigas Root is available and quoted.

How is Korean angelica told apart from dong quai?

Angelica gigas is rich in decursin and decursinol angelate, which are low or absent in Angelica sinensis (dong quai) and Angelica acutiloba. The monograph lists these species as potential confounding materials.

Can decursin and decursinol angelate be separated?

They are isomers with the same mass, so they are separated chromatographically and identified by retention time against reference standards.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/442126

Identity facts from the USP monograph header for this compound.

Order

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