Kutki (Picrorhiza kurrooa)

Kutki: botanical (root and rhizome, iridoid markers).

Kutki testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of a Kutki marker compound

Marker compound: 2D structure drawn from the PubChem record (CID 6440892).

Compound data

Botanical source

Picrorhiza Species Root and Rhizome

Marker compounds

picroside I, picroside II

Basis

total or named markers, as your specification states

Type

Botanical (root and rhizome, iridoid markers)

Structure and names

Marker compounds: picroside I (CAS 27409-30-9), picroside II (CAS 39012-20-9)

How Vanguard tests Kutki

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (picroside I and picroside II), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by HPTLC and HPLC retention time, botanical characteristics, and content of picroside I and picroside II by HPLC. Full testing to the USP Picrorhiza Species Root and Rhizome monograph is available and quoted.

What's reported

  • Marker compounds, as % w/w on the basis your specification states
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Picrorhiza Species Root and Rhizome
  • Picrorhiza Species Root and Rhizome Dry Extract
  • Picrorhiza Species Root and Rhizome Powder
  • Picrorhiza kurrooa Root and Rhizome
  • Picrorhiza kurrooa Root and Rhizome Dry Extract
  • Picrorhiza kurrooa Root and Rhizome Powder
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Kutki testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of picroside I and picroside II, with LC-MS identity. Full testing to the USP Picrorhiza Species Root and Rhizome monograph is available and quoted.

What are picroside I and II?

Picroside I and picroside II are iridoid glycosides characteristic of kutki root and rhizome, and the monograph sums them as iridoid glycosides on an anhydrous basis.

What is kutki adulterated with?

Related Picrorhiza species and unrelated roots can be sold as kutki. The picroside profile and HPTLC fingerprint help confirm the material.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/6440892

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.