Levamisole hydrochloride

Levamisole hydrochloride: imidazothiazole anthelmintic.

Levamisole hydrochloride testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Levamisole hydrochloride: 2D structure drawn from the PubChem record (CID 27944).

Compound data

CAS number

16595-80-5

Formula

C₁₁H₁₂N₂S · HCl

Molecular weight

240.75 g/mol

Type

Imidazothiazole anthelmintic

Structure and names

Identity: Levamisole hydrochloride

IUPAC name: (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride

How Vanguard tests Levamisole hydrochloride

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, thin-layer chromatography and a chloride test, assay by titration, chromatographic purity by thin-layer chromatography, plus specific rotation, UV absorbance, melting range, pH, color and completeness of solution, loss on drying and residue on ignition. Full testing to the USP Levamisole Hydrochloride monograph is available and quoted.

What's reported

Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Levamisole Hydrochloride (CAS 16595-80-5)
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Levamisole hydrochloride testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay and LC-MS for identity. Full testing to the USP Levamisole Hydrochloride monograph is available and quoted.

What is the difference between levamisole and tetramisole?

Tetramisole is the racemic mixture and levamisole is its S-enantiomer. They have the same mass and the same retention time on a standard column, so the monograph uses specific rotation to confirm the single enantiomer, and a chiral HPLC method can be quoted.

The monograph uses TLC and titration. What does the $250 test add?

HPLC-UV gives a quantitative purity profile and assay in one run, and LC-MS confirms the identity by mass.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/27944

Identity facts from the USP monograph header for this compound.

Order

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