Tranexamic acid

Tranexamic acid: lysine analog (antifibrinolytic).

Tranexamic acid testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Tranexamic acid

Tranexamic acid: 2D structure drawn from the PubChem record (CID 5526).

Compound data

CAS number

1197-18-8

Formula

C8H15NO2

Molecular weight

157.21 g/mol

Type

Lysine analog (antifibrinolytic)

Structure and names

Identity: Tranexamic acid

IUPAC name: 4-(aminomethyl)cyclohexane-1-carboxylic acid

How Vanguard tests Tranexamic acid

Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, chloride and loss on drying. Full testing to the USP Tranexamic Acid monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Tranexamic Acid (CAS 1197-18-8)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Tranexamic acid testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Tranexamic Acid monograph is available and quoted.

What is the cis isomer and why does it matter?

Tranexamic acid is the trans isomer. The cis isomer has the same mass, so it is separated by HPLC and reported as a named impurity.

Tranexamic acid has weak UV absorbance. How is it measured?

It absorbs only at low UV wavelengths, so the lab uses a detection method suited to the compound.

What forms does tranexamic acid arrive in?

Usually as a white powder, and also in serums and creams. Finished products need extraction, so tell us the matrix.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/5526

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.