Aurothioglucose (gold thioglucose)

Aurothioglucose: gold compound (organogold salt).

Aurothioglucose testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Aurothioglucose: 2D structure drawn from the PubChem record (CID 6104).

Compound data

CAS number

12192-57-3

Formula

C₆H₁₁AuO₅S

Molecular weight

392.18 g/mol

Type

Gold compound (organogold salt)

Structure and names

Identity: Aurothioglucose

IUPAC name: gold(1+);(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate

How Vanguard tests Aurothioglucose

Method for the $250 identity, purity and quantity test: ICP-MS metal content, chromatographic assay of the thioglucose ligand, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by thin-layer chromatography and a chemical test, assay of gold by gravimetry, specific rotation and loss on drying. Full testing to the USP Aurothioglucose monograph is available and quoted.

What's reported

Metal content by ICP-MS, against the label or specification
Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Aurothioglucose (CAS 12192-57-3)
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Aurothioglucose testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by ICP-MS for gold content and a chromatographic method suited to the compound for the thioglucose part. Full testing to the USP Aurothioglucose monograph is available and quoted.

Why is gold content the main result for aurothioglucose?

The monograph defines the material by its gold content, and ICP-MS measures gold directly. The result can be compared with the gold fraction expected for the pure compound.

Does aurothioglucose degrade?

It is sensitive to light and air, and darkening can be a sign of breakdown. Keep samples sealed and protected from light before shipping.

Why is the thioglucose part harder to measure?

Thioglucose has no aromatic ring, so the lab uses a detection method suited to the compound.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/6104

Identity facts from the USP monograph header for this compound.

Order

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