Brompheniramine maleate: antihistamine (H1 antagonist, alkylamine).
Brompheniramine maleate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Brompheniramine maleate: 2D structure drawn from the PubChem record (CID 5281067).
980-71-2
C16H19BrN2 · C4H4O4
435.31 g/mol
Antihistamine (H1 antagonist, alkylamine)
Identity: Brompheniramine maleate
IUPAC name: 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioic acid
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, optical rotation, pH and loss on drying. Full testing to the USP Brompheniramine Maleate monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Brompheniramine Maleate monograph is available and quoted.
Yes. They differ only by bromine versus chlorine, so their masses and isotope patterns differ, and they separate by HPLC.
Yes. Maleate elutes early as its own peak and is not counted as an impurity of brompheniramine.
Dexbrompheniramine is the single active enantiomer. Standard HPLC gives the same result for both forms, so confirming the enantiomer needs a chiral method, which can be quoted separately.
https://pubchem.ncbi.nlm.nih.gov/compound/5281067
Identity facts from the USP monograph header for this compound.
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