Butoconazole nitrate: imidazole antifungal.
Butoconazole nitrate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Butoconazole nitrate: 2D structure drawn from the PubChem record (CID 47471).
64872-77-1
C19H17Cl3N2S · HNO3
474.79 g/mol
Imidazole antifungal
Identity: Butoconazole nitrate
IUPAC name: 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole;nitric acid
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy, assay by HPLC, ordinary impurities by thin-layer chromatography, residue on ignition and loss on drying. Full testing to the USP Butoconazole Nitrate monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Butoconazole Nitrate monograph is available and quoted.
LC-MS confirms the butoconazole cation by its mass and by the isotope pattern from its three chlorine atoms, which sets it apart from other imidazole antifungals.
Yes. The cream is extracted before HPLC, and the result is reported against the labeled strength.
https://pubchem.ncbi.nlm.nih.gov/compound/47471
Identity facts from the USP monograph header for this compound.
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