Carboprost tromethamine: prostaglandin (15-methyl PGF2 alpha analog).
Carboprost tromethamine testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Carboprost tromethamine: 2D structure drawn from the PubChem record (CID 5281074).
58551-69-2
C21H36O5 · C4H11NO3
489.65 g/mol
Prostaglandin (15-methyl PGF2 alpha analog)
Identity: Carboprost tromethamine
IUPAC name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid
Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, and residue on ignition, optical rotation and loss on drying. Full testing to the USP Carboprost monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Carboprost monograph is available and quoted.
Carboprost is supplied as a 1:1 salt with tromethamine, which adds about a quarter of the weight. Results are reported against the salt unless the free acid basis is requested.
Stereoisomers such as the 15-epimer and the 5,6-trans isomer can form during synthesis. They have the same mass as carboprost, so they are told apart by HPLC retention time rather than by mass.
Prostaglandins like carboprost degrade with heat, so samples should be shipped cold and tested promptly.
https://pubchem.ncbi.nlm.nih.gov/compound/5281074
Identity facts from the USP monograph header for this compound.
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