Carteolol hydrochloride

Carteolol hydrochloride: beta blocker.

Carteolol hydrochloride testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Carteolol hydrochloride

Carteolol hydrochloride: 2D structure drawn from the PubChem record (CID 40127).

Compound data

CAS number

51781-21-6

Formula

C16H24N2O3 · HCl

Molecular weight

328.83 g/mol

Type

Beta blocker

Structure and names

Identity: Carteolol hydrochloride

IUPAC name: 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one;hydrochloride

How Vanguard tests Carteolol hydrochloride

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, HPLC retention time and a chloride test, assay by HPLC, organic impurities by HPLC, and residue on ignition, pH and loss on drying. Full testing to the USP Carteolol monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Carteolol Hydrochloride (CAS 51781-21-6)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Carteolol hydrochloride testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Carteolol monograph is available and quoted.

Which impurity is typical for carteolol?

Dehydrocarteolol, an oxidized form of the quinolinone ring, is one of the related compounds named in the USP monograph. It appears as a separate peak in the HPLC purity profile.

Can carteolol eye drops be tested?

Yes. Ophthalmic solutions can be diluted and tested directly, and the carteolol hydrochloride content is reported against the label concentration.

Is the result reported as the hydrochloride salt?

Yes, by default. The hydrochloride makes up about 11 percent of the salt by weight, so tell us if you need results on the free base basis.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/40127

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.