Cefoxitin sodium: cephamycin antibiotic (second generation).
Cefoxitin sodium testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cefoxitin sodium: 2D structure drawn from the PubChem record (CID 23667300).
33564-30-6
C16H16N3NaO7S2
449.43 g/mol
Cephamycin antibiotic (second generation)
Identity: Cefoxitin sodium
IUPAC name: sodium (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by HPLC retention time, UV spectroscopy and a sodium test, assay by HPLC, acetone and methanol by gas chromatography, and optical rotation, pH, water, bacterial endotoxins and sterility. Full testing to the USP Cefoxitin monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cefoxitin monograph is available and quoted.
Cefoxitin can lose its carbamoyl group to form decarbamoylcefoxitin, and the beta-lactam ring can open with moisture. These appear as separate peaks in the HPLC profile.
These solvents can remain from crystallizing cefoxitin sodium. They are measured by GC, which is available and quoted.
Yes. It picks up moisture from air, which affects both weight and stability, so samples should stay sealed until testing.
https://pubchem.ncbi.nlm.nih.gov/compound/23667300
Identity facts from the USP monograph header for this compound.
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