Cefpodoxime proxetil: cephalosporin antibiotic (third generation, ester prodrug).
Cefpodoxime proxetil testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cefpodoxime proxetil: 2D structure drawn from the PubChem record (CID 6526396).
87239-81-4
C21H27N5O9S2
557.59 g/mol
Cephalosporin antibiotic (third generation, ester prodrug)
Identity: Cefpodoxime proxetil
IUPAC name: 1-propan-2-yloxycarbonyloxyethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared and UV spectroscopy and a color reaction, assay by HPLC, chromatographic purity by HPLC, and optical rotation, water, residue on ignition and the isomer ratio by HPLC. Full testing to the USP Cefpodoxime Proxetil monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cefpodoxime Proxetil monograph is available and quoted.
The proxetil ester has a chiral carbon, so the material is a mix of two diastereomers that separate on HPLC. Both peaks are summed for the assay and their ratio is reported.
Yes. The ester hydrolyzes to cefpodoxime acid, especially in solution. Cefpodoxime acid shows up as a separate peak, so samples are prepared fresh.
Usually powder, tablets or granules for oral suspension. Tell us the form so the right extraction is used.
https://pubchem.ncbi.nlm.nih.gov/compound/6526396
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
