Cephapirin: cephalosporin antibiotic (first generation, veterinary).
Cephapirin testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cephapirin: 2D structure drawn from the PubChem record (CID 23675312).
24356-60-3
C17H16N3NaO6S2
445.45 g/mol
Cephalosporin antibiotic (first generation, veterinary)
Identity: Cephapirin sodium
IUPAC name: sodium (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and a sodium test, assay by HPLC, and pH, water, sterility and bacterial endotoxins for cephapirin sodium, with benzathine content added for cephapirin benzathine. Full testing to the USP Cephapirin Sodium monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cephapirin Sodium monograph is available and quoted.
Cephapirin benzathine is a poorly soluble salt with two cephapirin units per benzathine, while the sodium salt dissolves readily. Their molecular weights differ widely, so results are reported against the form on the label.
Yes. Intramammary products are oily suspensions, so cephapirin is extracted from the oil base before HPLC and reported per syringe or per gram.
Cephapirin loses its acetyl group to form desacetylcephapirin, which appears as a separate peak in the HPLC profile.
https://pubchem.ncbi.nlm.nih.gov/compound/23675312
Identity facts from the USP monograph header for this compound.
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