Chloramphenicol: amphenicol antibiotic.
Chloramphenicol testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Chloramphenicol: 2D structure drawn from the PubChem record (CID 5959).
56-75-7
C11H12Cl2N2O5
323.13 g/mol
Amphenicol antibiotic
Identity: Chloramphenicol
IUPAC name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy, HPLC retention time, melting range and specific rotation, assay by HPLC, chromatographic purity by thin-layer chromatography, and pH, bacterial endotoxins and sterility. Full testing to the USP Chloramphenicol monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Chloramphenicol monograph is available and quoted.
Both are esters of chloramphenicol with much higher molecular weights, so the same mass contains less chloramphenicol. Tell us which form is on the label so the result is calculated correctly.
Yes. Chloramphenicol is the D-threo isomer, one of four possible stereoisomers. A standard HPLC purity test does not separate them, and chiral testing is quoted separately.
Hydrolysis of the amide gives 2-amino-1-(4-nitrophenyl)-1,3-propanediol, which shows up as a separate peak in the HPLC purity profile.
https://pubchem.ncbi.nlm.nih.gov/compound/5959
Identity facts from the USP monograph header for this compound.
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