Nifedipine: calcium channel blocker (dihydropyridine).
Nifedipine testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Nifedipine: 2D structure drawn from the PubChem record (CID 4485).
21829-25-4
C17H18N2O6
346.33 g/mol
Calcium channel blocker (dihydropyridine)
Identity: Nifedipine
IUPAC name: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, chloride and sulfate limit tests, a perchloric acid titration limit, and loss on drying. Full testing to the USP Nifedipine monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Nifedipine monograph is available and quoted.
Yes, strongly. Under daylight or UV light nifedipine converts to its nitrosophenylpyridine and nitrophenylpyridine analogs, which are its main related compounds. Samples should be kept in amber containers and prepared under low light.
Nifedipine arrives as raw powder, liquid-filled capsules or extended-release tablets. Each needs its own extraction, and light protection applies to all of them.
https://pubchem.ncbi.nlm.nih.gov/compound/4485
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
