Thiabendazole

Thiabendazole: benzimidazole anthelmintic and fungicide.

Thiabendazole testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Thiabendazole

Thiabendazole: 2D structure drawn from the PubChem record (CID 5430).

Compound data

CAS number

148-79-8

Formula

C10H7N3S

Molecular weight

201.25 g/mol

Type

Benzimidazole anthelmintic and fungicide

Structure and names

Identity: Thiabendazole

IUPAC name: 4-(1H-benzimidazol-2-yl)-1,3-thiazole

How Vanguard tests Thiabendazole

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared and UV spectroscopy, a color reaction and thin-layer chromatography, assay by nonaqueous titration, related compounds by thin-layer chromatography, residue on ignition, melting range, and loss on drying. Full testing to the USP Thiabendazole monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Thiabendazole (CAS 148-79-8)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Thiabendazole testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Thiabendazole monograph is available and quoted.

The USP assay is a titration. Why does the $250 test use HPLC?

A titration measures total basic content and does not separate thiabendazole from related compounds. HPLC gives a purity profile and a specific assay against a reference standard, and LC-MS confirms the mass.

Is thiabendazole also tested as a residue on produce?

Thiabendazole is also used as a postharvest fungicide, so it comes up in residue work. The $250 test is for raw material or product purity and content; trace residue analysis in foods is a separate method and is quoted.

Is thiabendazole stable?

Thiabendazole is fairly stable as a dry solid but can break down in solution under UV light. Any degradation shows up as extra peaks in the HPLC purity profile.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/5430

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.