Argireline, INCI name Acetyl Hexapeptide-8, is a synthetic hexapeptide cosmetic ingredient with an acetylated N-terminus and an amidated C-terminus (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2).
Argireline testing at Vanguard Laboratory: purity, quantity and identity of the raw peptide from $250 per vial, with results in 3 to 5 business days.
On this page: Testing · Compound data · Sequence · How we test it · Forms and references · FAQ
Every package includes purity, quantity, identity and a solubility check. Raw powder purity is $200 for a 50 mg sample.
$250
$550
$700
Each test can be added to a package or ordered on its own. Results arrive in 3 to 5 business days.
Included in every package
How pure the Argireline is and how much is in the vial: purity in area percent, quantity in mg per vial against the label. Details
Included in every package
Whether the sample contains Argireline, compared with a reference standard. Reported as match or no match. Details
Quoted
Whether the molecular mass matches Argireline, which helps catch look-alike products. Details
$70
How much TFA, acetate or chloride the powder contains. Other salt forms are quoted. Details
$150
Sterility for injectables: 1–10 unopened vials at the same sterility-test price. Bioburden for other forms. Included in Gold and Elite. Details
$200 per vial
Purity and routine identity by retention time and UV spectrum against a reference standard, without quantity: no mg per vial, concentration or label-claim result. 1 vial; 3 to 5 business days. LC-MS is quoted separately. Details
$360 per vial
Screen for semaglutide, tirzepatide and retatrutide without naming the expected peptide. Identity, amount and purity where reportable. Blind GLP-1 panel
Quoted
Which cysteines are paired, by Orbitrap high-resolution mass spectrometry of the digested peptide.
Quoted
Charge, polarity and size variants by ion-exchange, hydrophilic interaction and size-exclusion chromatography, alongside routine HPLC purity.
Quoted
Hydrolysis and amino acid analysis, to confirm composition and net peptide content.
Quoted
D- and L-forms of the amino acids, to check for racemization.
Orders of ten or more samples are 10% off.
acetylated, amidated linear hexapeptide
C34H60N14O12S (calculated from the sequence)
889.0 g/mol
Monoisotopic 888.42 Da
616204-22-9
Modifications: N-terminal acetyl group and C-terminal amide.
Other names: Acetyl Hexapeptide-8 (INCI), Acetyl Hexapeptide-3 (earlier INCI name)
Raw Argireline runs on the lab’s peptide purity and quantity method: reversed-phase HPLC on a C18 column with a water and acetonitrile gradient containing 0.1% TFA, and UV detection at 214 to 220 nm. Purity is the main peak’s share of the total peak area, quantity is measured against a reference standard, and identity is confirmed by retention time and UV spectrum against the same standard. LC-MS confirmation of the mass is quoted separately.
In finished creams and serums the peptide is present at low levels and the formula affects extraction, so finished-product assays are quoted; see topicals and cosmetics testing.
Send 1 vial or 50 mg of raw powder per sample; for a solution, tell us the claimed concentration. Results arrive in 3 to 5 business days.
Yes. SNAP-8 (Acetyl Octapeptide-3) has eight residues and a higher mass, so it separates from Argireline by HPLC and is distinct by LC-MS.
Yes, as a quoted assay. The peptide is extracted from the formula and measured by HPLC, with the result reported as % w/w against the label.
Methionine oxidation, which adds 16 Da, and deletion sequences from synthesis that are missing one residue. Both usually appear as separate peaks in the purity result.
Sequence per the INCI name Acetyl Hexapeptide-8; formula and weights calculated from the sequence. CAS number as cross-referenced in PubChem.
Start an order online, or send the compound name and the tests you need for a quote.
