Acepromazine maleate

Acepromazine maleate: phenothiazine.

Acepromazine maleate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Acepromazine maleate

Acepromazine maleate: 2D structure drawn from the PubChem record (CID 6420038).

Compound data

CAS number

3598-37-6

Formula

C19H22N2OS · C4H4O4

Molecular weight

442.53 g/mol

Type

Phenothiazine

Structure and names

Identity: Acepromazine maleate

IUPAC name: (Z)-but-2-enedioic acid;1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanone

How Vanguard tests Acepromazine maleate

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by thin-layer chromatography, residue on ignition, melting range, pH, and water content. Full testing to the USP Acepromazine Maleate monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Acepromazine Maleate (CAS 3598-37-6; free base CAS 61-00-7)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Acepromazine maleate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Acepromazine Maleate monograph is available and quoted.

Is acepromazine light sensitive?

Yes. Like other phenothiazines, acepromazine oxidizes under light and air to the sulfoxide, which appears as a separate peak in the HPLC purity profile. Samples should be kept dark.

Does the maleate show up in the HPLC test?

Maleic acid elutes early as its own peak and is not counted as an impurity of acepromazine. The report gives acepromazine as the salt or free base as requested.

Can the test tell acepromazine from chlorpromazine or promazine?

Yes. These phenothiazines differ in their side groups, so they separate by HPLC and differ in mass by LC-MS.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/6420038

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.