Acetohydroxamic acid

Acetohydroxamic acid: hydroxamic acid (urease inhibitor).

Acetohydroxamic acid testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Acetohydroxamic acid

Acetohydroxamic acid: 2D structure drawn from the PubChem record (CID 1990).

Compound data

CAS number

546-88-3

Formula

C2H5NO2

Molecular weight

75.07 g/mol

Type

Hydroxamic acid (urease inhibitor)

Structure and names

Identity: Acetohydroxamic acid

IUPAC name: N-hydroxyacetamide

How Vanguard tests Acetohydroxamic acid

Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and a color test, assay by visible spectrophotometry of the ferric chloride complex, a hydroxylamine limit by fluorometry, and residue on ignition and loss on drying. Full testing to the USP Acetohydroxamic Acid monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Acetohydroxamic Acid (CAS 546-88-3)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Acetohydroxamic acid testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Acetohydroxamic Acid monograph is available and quoted.

Why does the monograph check for hydroxylamine?

Hydroxylamine is a starting material and a breakdown product of acetohydroxamic acid, which can hydrolyze back to hydroxylamine and acetic acid. Its level is a useful sign of how a lot was made and stored.

Is acetohydroxamic acid easy to see with a standard UV detector?

It is a very small, polar molecule with weak UV absorbance, so the lab uses a detection method suited to the compound.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/1990

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.