Almotriptan malate: triptan (5-HT1B/1D agonist).
Almotriptan malate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Almotriptan malate: 2D structure drawn from the PubChem record (CID 123607).
181183-52-8
C17H25N3O2S · C4H6O5
469.55 g/mol
Triptan (5-HT1B/1D agonist)
Identity: Almotriptan malate
IUPAC name: N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine;2-hydroxybutanedioic acid
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities and fumaric acid by HPLC, and residue on ignition and water. Full testing to the USP Almotriptan Malate monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Almotriptan Malate monograph is available and quoted.
Fumaric acid is a common impurity in malic acid and can also form from it, so it reflects the quality of the malate counter-ion. It is measured separately from the drug-related impurities.
The USP material is the malate salt, and the assay is reported on that basis unless you ask for free base. Tablet labels usually state strength as almotriptan base, so tell us which you need.
https://pubchem.ncbi.nlm.nih.gov/compound/123607
Identity facts from the USP monograph header for this compound.
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