Amiloxate (isoamyl p-methoxycinnamate)

Amiloxate: sunscreen UV filter.

Amiloxate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Amiloxate: 2D structure drawn from the PubChem record (CID 92386).

Compound data

CAS number

71617-10-2

Formula

C₁₅H₂₀O₃

Molecular weight

248.32 g/mol

Type

Sunscreen UV filter

Structure and names

Identity: Amiloxate

IUPAC name: 3-methylbutyl 3-(4-methoxyphenyl)prop-2-enoate

How Vanguard tests Amiloxate

Method for the $250 identity, purity and quantity test: GC-FID assay and purity, GC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, UV and GC retention time, assay by GC, impurities by GC, and specific gravity, refractive index and acidity. Full testing to the USP Amiloxate monograph is available and quoted.

What's reported

Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Amiloxate (CAS 71617-10-2)
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Amiloxate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by GC-FID for assay and purity, and GC-MS for identity. Full testing to the USP Amiloxate monograph is available and quoted.

Why is amiloxate tested by GC?

Amiloxate is an oily ester, and the USP monograph uses gas chromatography for its assay and impurities. GC-MS gives the identity in the same type of run.

Does light change amiloxate?

Like other cinnamate UV filters, it can convert from the trans to the cis isomer in light. The isomers separate on the GC run, so light exposure shows up in the purity result.

Can amiloxate be tested in a sunscreen?

Yes, it can be extracted from a lotion or cream and measured, but other UV filters in the formula need to be separated first. Send the label so the method can account for them.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/92386

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.

All research compounds