Aminolevulinic acid hydrochloride

Aminolevulinic acid hydrochloride: amino keto acid (porphyrin precursor).

Aminolevulinic acid hydrochloride testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Aminolevulinic acid hydrochloride

Aminolevulinic acid hydrochloride: 2D structure drawn from the PubChem record (CID 123608).

Compound data

CAS number

5451-09-2

Formula

C5H9NO3 · HCl

Molecular weight

167.59 g/mol

Type

Amino keto acid (porphyrin precursor)

Structure and names

Identity: Aminolevulinic acid hydrochloride

IUPAC name: 5-amino-4-oxopentanoic acid;hydrochloride

How Vanguard tests Aminolevulinic acid hydrochloride

Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, HPLC retention time and a chloride test, assay by HPLC, organic impurities by HPLC, and residue on ignition, pH and loss on drying. Full testing to the USP Aminolevulinic Acid Hydrochloride monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Aminolevulinic Acid Hydrochloride (CAS 5451-09-2)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Aminolevulinic acid hydrochloride testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Aminolevulinic Acid Hydrochloride monograph is available and quoted.

Is aminolevulinic acid stable in solution?

It is stable as the dry hydrochloride, but in neutral or basic solution two molecules condense into a pyrazine dimer. Solutions should be acidic and fresh, and the dimer is reported as an impurity.

Why is a UV detector a challenge here?

Aminolevulinic acid has no aromatic ring and absorbs only weakly in the UV, so the lab uses a detection method suited to the compound.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/123608

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.