Antazoline phosphate

Antazoline phosphate: imidazoline antihistamine.

Antazoline phosphate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Antazoline phosphate

Antazoline phosphate: 2D structure drawn from the PubChem record (CID 158798).

Compound data

CAS number

154-68-7

Formula

C17H19N3 · H3PO4

Molecular weight

363.35 g/mol

Type

Imidazoline antihistamine

Structure and names

Identity: Antazoline phosphate

IUPAC name: N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline;phosphoric acid

How Vanguard tests Antazoline phosphate

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, and pH and loss on drying. Full testing to the USP Antazoline Phosphate monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Antazoline Phosphate (CAS 154-68-7)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Antazoline phosphate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Antazoline Phosphate monograph is available and quoted.

Is the result reported as antazoline or antazoline phosphate?

The USP material is the phosphate salt, and results are reported on that basis unless you ask for the free base. The phosphate adds a noticeable share of the weight.

What form does antazoline usually arrive in?

It is most often a powder or an eye drop, where it is commonly combined with a decongestant such as naphazoline. In combination products both compounds are separated on the HPLC run.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/158798

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.