Benoxinate hydrochloride: local anesthetic (ester type).
Benoxinate hydrochloride testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Benoxinate hydrochloride: 2D structure drawn from the PubChem record (CID 6420040).
5987-82-6
C17H28N2O3 · HCl
344.88 g/mol
Local anesthetic (ester type)
Identity: Benoxinate hydrochloride
IUPAC name: 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate;hydrochloride
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared and UV spectroscopy and a chloride test, assay by titration, ordinary impurities by thin-layer chromatography, residue on ignition, pH and loss on drying. Full testing to the USP Benoxinate Hydrochloride monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Benoxinate Hydrochloride monograph is available and quoted.
Yes. Benoxinate is the USP name and oxybuprocaine is the international name for the same compound.
As an ester, benoxinate can hydrolyze in solution to its aminobenzoic acid part and an amino alcohol. The acid shows as a separate peak in the HPLC purity profile.
Yes. Ophthalmic solutions are diluted to a working concentration, and the result is compared with the labeled strength.
https://pubchem.ncbi.nlm.nih.gov/compound/6420040
Identity facts from the USP monograph header for this compound.
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