Betamethasone: corticosteroid (glucocorticoid).
Betamethasone testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Betamethasone: 2D structure drawn from the PubChem record (CID 9782).
378-44-9
C22H29FO5
392.46 g/mol
Corticosteroid (glucocorticoid)
Identity: Betamethasone
IUPAC name: (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP Betamethasone monograph covers identity by infrared spectroscopy and thin-layer chromatography, assay by HPLC, ordinary impurities by thin-layer chromatography, specific rotation, loss on drying, and residue on ignition. Full testing to the USP Betamethasone monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Betamethasone monograph is available and quoted.
They are stereoisomers with the same mass, differing only at the 16-methyl position, so LC-MS alone cannot separate them. The HPLC method is set up to resolve the two by retention time.
Yes. Each ester has its own retention time and mass, so the report names the ester found and gives quantity for that ester.
Powders, creams, ointments and injectable suspensions. Creams and ointments need an extraction step, so send the labeled strength with the sample.
https://pubchem.ncbi.nlm.nih.gov/compound/9782
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
