Bhumi amla (Phyllanthus amarus)

Bhumi amla: botanical (aerial parts, lignan markers).

Bhumi amla testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of a Bhumi amla marker compound

Marker compound: 2D structure drawn from the PubChem record (CID 358901).

Compound data

Botanical source

Phyllanthus amarus Aerial Parts

Marker compounds

phyllanthin, hypophyllanthin

Basis

total or named markers, as your specification states

Type

Botanical (aerial parts, lignan markers)

Structure and names

Marker compounds: phyllanthin (CAS 10351-88-9), hypophyllanthin (CAS 33676-00-5)

How Vanguard tests Bhumi amla

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (phyllanthin and hypophyllanthin), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of phyllanthin and hypophyllanthin by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Phyllanthus amarus Aerial Parts is available and quoted.

What's reported

  • Marker compounds, as % w/w on the basis your specification states
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Phyllanthus amarus Aerial Parts
  • Phyllanthus amarus Aerial Parts Powder
  • Phyllanthus amarus Aerial Parts Powdered Extract
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Bhumi amla testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of phyllanthin and hypophyllanthin, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Phyllanthus amarus Aerial Parts is available and quoted.

Can other Phyllanthus species be told apart?

Phyllanthus niruri, P. urinaria and P. fraternus are often mixed up with P. amarus. Phyllanthin and hypophyllanthin are characteristic of P. amarus and are low or absent in several look-alikes.

What form do samples usually arrive in?

Usually dried whole herb, powder, powdered extract or capsules. Whole herb includes stems, leaves and fruit, so it is ground fully before extraction.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/358901

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.