Brimonidine tartrate: alpha-2 adrenergic agonist.
Brimonidine tartrate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Brimonidine tartrate: 2D structure drawn from the PubChem record (CID 54405).
70359-46-5
C11H10BrN5 · C4H6O6
442.22 g/mol
Alpha-2 adrenergic agonist
Identity: Brimonidine tartrate
IUPAC name: 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine;(2R,3R)-2,3-dihydroxybutanedioic acid
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, optical rotation and loss on drying. Full testing to the USP Brimonidine Tartrate monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Brimonidine Tartrate monograph is available and quoted.
Eye drops are usually labeled as brimonidine tartrate, so that is the default basis. Tartrate is about a third of the salt's weight, so the basis matters.
Yes. Preservatives such as benzalkonium chloride separate from brimonidine by HPLC, and the result is compared with the labeled concentration.
https://pubchem.ncbi.nlm.nih.gov/compound/54405
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
