Carbinoxamine maleate

Carbinoxamine maleate: antihistamine (ethanolamine H1 blocker).

Carbinoxamine maleate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Carbinoxamine maleate

Carbinoxamine maleate: 2D structure drawn from the PubChem record (CID 5282409).

Compound data

CAS number

3505-38-2

Formula

C16H19ClN2O · C4H4O4

Molecular weight

406.86 g/mol

Type

Antihistamine (ethanolamine H1 blocker)

Structure and names

Identity: Carbinoxamine maleate

IUPAC name: (Z)-but-2-enedioic acid;2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine

How Vanguard tests Carbinoxamine maleate

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy, UV spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, and residue on ignition, pH and loss on drying. Full testing to the USP Carbinoxamine monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Carbinoxamine Maleate (CAS 3505-38-2)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Carbinoxamine maleate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Carbinoxamine monograph is available and quoted.

Is the result reported as carbinoxamine or carbinoxamine maleate?

The material is normally the maleate salt, and results are reported against the salt unless you ask for the free base. The maleate counter-ion makes up about 29 percent of the salt by weight, so the basis matters when comparing to a label.

Does maleic acid show up in the HPLC purity profile?

Maleic acid from the salt elutes as its own early peak and is not counted as an impurity of carbinoxamine. Related compounds from synthesis and degradation are reported separately.

Is carbinoxamine a single enantiomer?

Carbinoxamine maleate is a racemic mixture. The standard HPLC purity test does not separate the enantiomers, and chiral testing is quoted separately.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/5282409

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.