Carprofen

Carprofen: nSAID (carbazole propionic acid, veterinary).

Carprofen testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Carprofen: 2D structure drawn from the PubChem record (CID 2581).

Compound data

CAS number

53716-49-7

Formula

C₁₅H₁₂ClNO₂

Molecular weight

273.71 g/mol

Type

NSAID (carbazole propionic acid, veterinary)

Structure and names

Identity: Carprofen

IUPAC name: 2-(6-chloro-9H-carbazol-2-yl)propanoic acid

How Vanguard tests Carprofen

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, and residue on ignition and loss on drying. Full testing to the USP Carprofen monograph is available and quoted.

What's reported

Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Carprofen (CAS 53716-49-7)
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Carprofen testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Carprofen monograph is available and quoted.

Is carprofen a racemic mixture?

Yes. Carprofen is a racemic mixture of the R and S enantiomers. A standard HPLC purity test does not separate them, and chiral testing is quoted separately.

What forms does carprofen arrive in?

Usually powder, caplets or flavored chewable tablets made for veterinary use. Chewable tablets contain flavor and binder ingredients, so they are extracted before HPLC and the result is reported per tablet.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/2581

Identity facts from the USP monograph header for this compound.

Order

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