Carvedilol: beta blocker (nonselective, with alpha-1 blocking).
Carvedilol testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Carvedilol: 2D structure drawn from the PubChem record (CID 2585).
72956-09-3
C24H26N2O4
406.47 g/mol
Beta blocker (nonselective, with alpha-1 blocking)
Identity: Carvedilol
IUPAC name: 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by three HPLC procedures, residue on ignition, and loss on drying. Full testing to the USP Carvedilol monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Carvedilol monograph is available and quoted.
Yes. Carvedilol has one stereocenter and is supplied as a racemic mixture. The standard HPLC test reports total carvedilol; separating the enantiomers needs a chiral method, which is quoted separately.
Yes. Some extended-release products use carvedilol phosphate. The same carvedilol ion is measured, and the result is converted to the salt using molecular weights.
https://pubchem.ncbi.nlm.nih.gov/compound/2585
Identity facts from the USP monograph header for this compound.
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