Cefadroxil: cephalosporin antibiotic (first generation).
Cefadroxil testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cefadroxil: 2D structure drawn from the PubChem record (CID 47964).
66592-87-8
C16H17N3O5S · H2O
381.40 g/mol
Cephalosporin antibiotic (first generation)
Identity: Cefadroxil (monohydrate)
IUPAC name: (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC and N,N-dimethylaniline by GC, and optical rotation, pH and water. Full testing to the USP Cefadroxil monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cefadroxil monograph is available and quoted.
Cefadroxil exists as a monohydrate, a hemihydrate and an anhydrous form, each with a different molecular weight. Results are calculated on the anhydrous basis, so water content and the form on the label both matter.
N,N-Dimethylaniline can be left over from cephalosporin synthesis. The USP monograph limits it with a separate GC test, which is available and quoted.
Usually powder, capsules, tablets or powder for oral suspension. Capsule contents and tablets are extracted and the result is reported per unit.
https://pubchem.ncbi.nlm.nih.gov/compound/47964
Identity facts from the USP monograph header for this compound.
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