Cefotaxime sodium: cephalosporin antibiotic (third generation).
Cefotaxime sodium testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cefotaxime sodium: 2D structure drawn from the PubChem record (CID 10695961).
64485-93-4
C16H16N5NaO7S2
477.45 g/mol
Cephalosporin antibiotic (third generation)
Identity: Cefotaxime sodium
IUPAC name: sodium (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy, HPLC retention time and a sodium test, assay by HPLC, organic impurities by two HPLC procedures, and optical rotation, pH, loss on drying, sterility and bacterial endotoxins. Full testing to the USP Cefotaxime monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cefotaxime monograph is available and quoted.
Cefotaxime loses its acetyl group to form desacetylcefotaxime, which can go on to form a lactone. Both appear as separate peaks in the HPLC purity profile.
Cefotaxime is reasonably stable as a dry powder but breaks down within hours to days once dissolved. Reconstituted samples should be refrigerated and tested quickly.
USP expresses content as cefotaxime. Tell us if you need the result on the sodium salt basis as labeled.
https://pubchem.ncbi.nlm.nih.gov/compound/10695961
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
