Cefprozil

Cefprozil: cephalosporin antibiotic (second generation).

Cefprozil testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Cefprozil

Cefprozil: 2D structure drawn from the PubChem record (CID 6436628).

Compound data

CAS number

121123-17-9

Formula

C18H19N3O5S · H2O

Molecular weight

407.44 g/mol

Type

Cephalosporin antibiotic (second generation)

Structure and names

Identity: Cefprozil (monohydrate)

IUPAC name: (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate

How Vanguard tests Cefprozil

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by two HPLC procedures, and pH, water and the E-isomer ratio by HPLC. Full testing to the USP Cefprozil monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Cefprozil (CAS 121123-17-9; anhydrous CAS 92665-29-7)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Cefprozil testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cefprozil monograph is available and quoted.

Why does cefprozil have Z and E isomers?

Cefprozil has a propenyl double bond, so it exists as a Z isomer, the main form, and a smaller E isomer. The two are separated by HPLC and the ratio is part of the USP monograph.

Is cefprozil reported as the monohydrate?

Cefprozil is supplied as the monohydrate, and USP expresses content on the anhydrous basis. Water content links the two.

What forms does cefprozil arrive in?

Usually powder, tablets or powder for oral suspension. Each is extracted before HPLC.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/6436628

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.