Chinese skullcap (Scutellaria baicalensis)

Chinese skullcap: botanical (flavonoid-rich root).

Chinese skullcap testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Marker compound: 2D structure drawn from the PubChem record (CID 64982).

Compound data

Botanical source

Scutellaria baicalensis Root

Marker compounds

baicalin, wogonoside (wogonin 7-O-glucuronide, CAS 51059-44-0)

Basis

total or named markers, as your specification states

Type

Botanical (flavonoid-rich root)

Structure and names

Marker compounds: baicalin (CAS 21967-41-9), wogonoside (wogonin 7-O-glucuronide, CAS 51059-44-0)

How Vanguard tests Chinese skullcap

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (baicalin and wogonoside), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of baicalin and wogonoside by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Scutellaria baicalensis Root is available and quoted.

What's reported

Marker compounds, as % w/w on the basis your specification states
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Scutellaria baicalensis Root
Scutellaria baicalensis Root Dry Extract
Scutellaria baicalensis Root Powder
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Chinese skullcap testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of baicalin and wogonoside, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Scutellaria baicalensis Root is available and quoted.

Is Chinese skullcap the same as American skullcap?

No. American skullcap is Scutellaria lateriflora, an aerial-part herb with a different flavonoid profile. Root material high in baicalin and wogonoside is characteristic of Scutellaria baicalensis.

Why can baicalin levels drop in stored root?

Enzymes in the root can hydrolyze baicalin to baicalein, especially if the root gets damp. Measuring baicalein along with baicalin shows whether this conversion has happened.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/64982

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.

All research compounds