Cidofovir: antiviral (acyclic nucleoside phosphonate).
Cidofovir testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cidofovir: 2D structure drawn from the PubChem record (CID 60613).
113852-37-2
C8H14N3O6P
279.19 g/mol
Antiviral (acyclic nucleoside phosphonate)
Identity: Cidofovir (anhydrous)
IUPAC name: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities and enantiomeric purity by HPLC, and water, pH, microbial enumeration and tests for specified microorganisms. Full testing to the USP Cidofovir monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and assay, with LC-MS to confirm identity. Full testing to the USP Cidofovir monograph is available and quoted.
Cidofovir drug substance is usually the dihydrate, and the monograph gives formulas for both forms. Water content is measured so the assay can be reported on the anhydrous basis or as is.
No. Cidofovir is a single enantiomer, and the monograph uses a separate chiral HPLC procedure for the other enantiomer. Chiral testing is quoted separately from the $250 test.
It is a very polar phosphonic acid, so it elutes early on a standard C18 column. Ion-pairing or highly aqueous conditions are used to hold it back from the solvent front.
https://pubchem.ncbi.nlm.nih.gov/compound/60613
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
